LANCL2

LANCL2
Identifiers
Aliases	LANCL2, GPR69B, TASP, LanC like 2
External IDs	OMIM: 612919; MGI: 1919085; HomoloGene: 23116; GeneCards: LANCL2; OMA:LANCL2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	55,433,737 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	57,716,424 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; lateral nuclear group of thalamus; ; gonad; ; entorhinal cortex; ; postcentral gyrus; ; superior frontal gyrus; ; prefrontal cortex; ; Brodmann area 23; ; sperm; ; endothelial cell;
	Top expressed in
	spermatocyte; ; spermatid; ; seminiferous tubule; ; subiculum; ; barrel cortex; ; genital tubercle; ; medial ganglionic eminence; ; prefrontal cortex; ; facial motor nucleus; ; tail of embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phosphatidylinositol-4-phosphate binding; phosphatidylinositol-5-phosphate binding; GTP binding; protein binding; ATP binding; phosphatidylinositol-3-phosphate binding; catalytic activity;
Cellular component	cytosol; plasma membrane; membrane; nucleus; cortical actin cytoskeleton; cytoplasm;
Biological process	positive regulation of abscisic acid-activated signaling pathway; negative regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	55915
	71835
	ENSG00000132434
	ENSMUSG00000062190
	Q9NS86
	Q9JJK2
	NM_018697
	NM_133737
	NP_061167
	NP_598498
	Wikidata
View/Edit Human	View/Edit Mouse

LanC-like protein 2 is a protein that in humans is encoded by the LANCL2 gene. It is a protein broadly expressed in the plasma a nuclear membranes of immune, epithelial and muscle cells and a potential therapeutic target for chronic inflammatory, metabolic and immune-mediated diseases such as Crohn's disease and diabetes.