LDB1

LDB1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XJY, 2XJZ, 2YPA
Identifiers
Aliases	LDB1, CLIM2, NLI, CLIM-2, LDB-1, LIM domain binding 1
External IDs	OMIM: 603451; MGI: 894762; HomoloGene: 2891; GeneCards: LDB1; OMA:LDB1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	102,120,368 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	46,033,653 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; ganglionic eminence; ; left ovary; ; skin of leg; ; gastric mucosa; ; skin of abdomen; ; right ovary; ; canal of the cervix; ; sural nerve; ; body of uterus;
	Top expressed in
	ventricular zone; ; tail of embryo; ; lip; ; genital tubercle; ; thymus; ; epiblast; ; yolk sac; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; neural layer of retina;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein homodimerization activity; transcription corepressor activity; LIM domain binding; chromatin binding; protein self-association; protein binding; cis-regulatory region sequence-specific DNA binding; enzyme binding; transcription coregulator activity;
Cellular component	transcription regulator complex; nucleus; cell leading edge; nucleoplasm; beta-catenin-TCF complex; protein-containing complex;
Biological process	hair follicle development; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; epithelial structure maintenance; regulation of transcription, DNA-templated; positive regulation of hemoglobin biosynthetic process; somatic stem cell population maintenance; regulation of transcription by RNA polymerase II; gastrulation with mouth forming second; cerebellar Purkinje cell differentiation; regulation of DNA-templated transcription, elongation; head development; histone H3-K4 acetylation; Wnt signaling pathway; transcription by RNA polymerase II; transcription, DNA-templated; cerebellum development; negative regulation of erythrocyte differentiation; multicellular organism development; neuron differentiation; anterior/posterior axis specification; cellular component assembly; negative regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; positive regulation of cell adhesion; regulation of focal adhesion assembly; regulation of cell migration; regulation of kinase activity; regulation of hematopoietic stem cell differentiation; negative regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	8861
	16825
	ENSG00000198728
	ENSMUSG00000025223
	Q86U70
	P70662
	NM_001113407; NM_003893; NM_001321612
	NM_001113408; NM_010697; NM_001360336
	NP_001106878; NP_001308541; NP_003884
	NP_001106879; NP_034827; NP_001347265
	Wikidata
View/Edit Human	View/Edit Mouse

LIM domain-binding protein 1 is a protein that in humans is encoded by the LDB1 gene.