LIAS (gene)

LIAS
Identifiers
Aliases	LIAS, LAS, LIP1, LS, PDHLD, HUSSY-01, HGCLAS, lipoic acid synthetase
External IDs	OMIM: 607031; MGI: 1934604; HomoloGene: 4997; GeneCards: LIAS; OMA:LIAS - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	39,485,109 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	65,568,036 bp
RNA expression pattern
	Top expressed in
	gonad; ; muscle of thigh; ; gastrocnemius muscle; ; rectum; ; right testis; ; right lobe of liver; ; left testis; ; right adrenal gland; ; body of pancreas; ; mucosa of transverse colon;
	Top expressed in
	facial motor nucleus; ; medullary collecting duct; ; olfactory epithelium; ; hair follicle; ; brown adipose tissue; ; otic vesicle; ; lacrimal gland; ; saccule; ; otic placode; ; digastric muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; 4 iron, 4 sulfur cluster binding; iron-sulfur cluster binding; catalytic activity; metal ion binding; lipoate synthase activity; sulfurtransferase activity;
Cellular component	mitochondrial matrix; mitochondrion;
Biological process	cellular nitrogen compound metabolic process; lipoate biosynthetic process; protein lipoylation; neural tube closure; inflammatory response; response to oxidative stress; response to lipopolysaccharide;
	Sources:Amigo / QuickGO
Orthologs
	11019
	79464
	ENSG00000121897
	ENSMUSG00000029199
	O43766
	Q99M04
NM_001278590; NM_001278591; NM_001278592; NM_006859; NM_194451;
	NM_001363700
	NM_024471; NM_001310612
NP_001265519; NP_001265520; NP_001265521; NP_006850; NP_919433;
	NP_001350629
	NP_001297541; NP_077791
	Wikidata
View/Edit Human	View/Edit Mouse

Lipoic acid synthetase is a protein that in humans is encoded by the LIAS gene.