LIME1

LIME1
Identifiers
Aliases	LIME1, LIME, LP8067, dJ583P15.4, Lck interacting transmembrane adaptor 1
External IDs	OMIM: 609809; MGI: 1919949; HomoloGene: 56785; GeneCards: LIME1; OMA:LIME1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	181,025,421 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; blood; ; spleen; ; putamen; ; bone marrow cells; ; kidney; ; caudate nucleus; ; nucleus accumbens; ; pituitary gland; ; hippocampus proper;
	Top expressed in
	granulocyte; ; islet of Langerhans; ; spleen; ; bone marrow; ; cerebellar cortex; ; thymus; ; Hypothalamus; ; striatum of neuraxis; ; olfactory bulb; ; superior frontal gyrus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein kinase binding;
Cellular component	integral component of membrane; plasma membrane; membrane; extracellular space; U2-type post-mRNA release spliceosomal complex; B cell receptor complex;
Biological process	B cell receptor signaling pathway; T cell receptor signaling pathway; adaptive immune response; immune system process; spliceosomal complex disassembly; regulation of transcription by RNA polymerase II; regulation of phosphatidylinositol 3-kinase signaling; regulation of I-kappaB kinase/NF-kappaB signaling; regulation of MAP kinase activity; regulation of release of sequestered calcium ion into cytosol; regulation of NIK/NF-kappaB signaling;
	Sources:Amigo / QuickGO
Orthologs
	54923
	72699
	n/a
	ENSMUSG00000090077
	Q9H400
	Q9EQR5
	NM_017806; NM_001305654; NM_001305655
	NM_023684
	NP_001292583; NP_001292584; NP_060276
	NP_076173
	Wikidata
View/Edit Human	View/Edit Mouse

Lck-interacting transmembrane adapter 1 is a protein that in humans is encoded by the LIME1 gene.

LIME1 is a raft-associated transmembrane adaptor phosphoprotein that is preferentially expressed in hemopoietic cells, particularly T cells.