LIMK1

LIMK1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3S95, 5L6W, 5HVK, 5HVJ
Identifiers
Aliases	LIMK1, LIMK, LIMK-1, LIM domain kinase 1
External IDs	OMIM: 601329; MGI: 104572; HomoloGene: 1738; GeneCards: LIMK1; OMA:LIMK1 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	74,122,525 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	134,717,452 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; right frontal lobe; ; cingulate gyrus; ; anterior cingulate cortex; ; prefrontal cortex; ; Amygdala; ; Brodmann area 9; ; granulocyte; ; ganglionic eminence; ; monocyte;
	Top expressed in
	motor neuron; ; gastrula; ; internal carotid artery; ; decidua; ; substantia nigra; ; external carotid artery; ; pontine nuclei; ; medial vestibular nucleus; ; anterior horn of spinal cord; ; supraoptic nucleus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; heat shock protein binding; metal ion binding; kinase activity; protein binding; protein heterodimerization activity; ATP binding; protein kinase activity; protein serine/threonine kinase activity; signal transducer activity;
Cellular component	membrane; focal adhesion; cytoplasm; nucleus; Golgi apparatus; cytosol; nuclear speck; neuron projection; lamellipodium; cell projection;
Biological process	Fc-gamma receptor signaling pathway involved in phagocytosis; phosphorylation; nervous system development; negative regulation of ubiquitin-protein transferase activity; Rho protein signal transduction; positive regulation of actin filament bundle assembly; actin cytoskeleton organization; signal transduction; positive regulation of axon extension; protein phosphorylation; positive regulation of stress fiber assembly;
	Sources:Amigo / QuickGO
Orthologs
	3984
	16885
	ENSG00000106683
	ENSMUSG00000029674
	P53667
	P53668
	NM_016735; NM_001204426; NM_002314
	NM_010717; NM_001305875
	NP_001191355; NP_002305
	NP_001292804; NP_034847
	Wikidata
View/Edit Human	View/Edit Mouse

LIM domain kinase 1 is an enzyme that in humans is encoded by the LIMK1 gene.