LMO1

LMO1
Identifiers
Aliases	LMO1, RBTN1, RHOM1, TTG1, LIM domain only 1
External IDs	OMIM: 186921; MGI: 102812; HomoloGene: 48101; GeneCards: LMO1; OMA:LMO1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	8,268,716 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	108,774,414 bp
RNA expression pattern
	Top expressed in
	gonad; ; vastus lateralis muscle; ; muscle of thigh; ; oocyte; ; testicle; ; retinal pigment epithelium; ; secondary oocyte; ; biceps brachii; ; islet of Langerhans; ; gastrocnemius muscle;
	Top expressed in
	medial ganglionic eminence; ; wall of urinary bladder; ; mucosa of urinary bladder; ; transitional epithelium of urinary bladder; ; primary oocyte; ; zygote; ; lip; ; secondary oocyte; ; facial motor nucleus; ; superior cervical ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; metal ion binding;
Cellular component	nucleus; nucleoplasm;
Biological process	regulation of T cell homeostatic proliferation; negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; regulation of hematopoietic stem cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	4004
	109594
	ENSG00000166407
	ENSMUSG00000036111
	P25800
	Q924W9
	NM_001270428; NM_002315
	NM_001302205; NM_001302206; NM_057173; NM_001382564
	NP_001257357; NP_002306
	NP_001289134; NP_001289135; NP_476514; NP_001369493
	Wikidata
View/Edit Human	View/Edit Mouse

Rhombotin-1 is a protein that in humans is encoded by the LMO1 gene.

LMO1 encodes a cysteine-rich, two LIM domain transcriptional regulator. It is mapped to an area of consistent chromosomal translocation in chromosome 11, disrupting it in T-cell leukemia, although more rarely than the related gene, LMO2 is disrupted.