LPCAT1

LPCAT1
Identifiers
Aliases	LPCAT1, lysophosphatidylcholine acyltransferase 1, AYTL2, PFAAP3, lpcat, AGPAT10, AGPAT9, LPCAT-1, lysoPAFAT
External IDs	OMIM: 610472; MGI: 2384812; HomoloGene: 9871; GeneCards: LPCAT1; OMA:LPCAT1 - orthologs
EC number	2.3.1.67
Gene location (Human)
Chr.	Chromosome 5 (human)
End	1,523,962 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	73,664,541 bp
RNA expression pattern
	Top expressed in
	upper lobe of left lung; ; spleen; ; ventricular zone; ; granulocyte; ; right lung; ; ganglionic eminence; ; blood; ; lymph node; ; monocyte; ; appendix;
	Top expressed in
	left lung; ; left lung lobe; ; Rostral migratory stream; ; right lung; ; right lung lobe; ; retinal pigment epithelium; ; tibiofemoral joint; ; ciliary body; ; primary oocyte; ; fetal liver hematopoietic progenitor cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	1-alkylglycerophosphocholine O-acyltransferase activity; metal ion binding; calcium ion binding; transferase activity; acyltransferase activity; 1-alkylglycerophosphocholine O-acetyltransferase activity; 1-alkenylglycerophosphocholine O-acyltransferase activity; 1-acylglycerophosphocholine O-acyltransferase activity; 1-acylglycerol-3-phosphate O-acyltransferase activity; 2-acylglycerol-3-phosphate O-acyltransferase activity;
Cellular component	integral component of membrane; Golgi apparatus; Golgi membrane; membrane; lipid droplet; endoplasmic reticulum membrane; endoplasmic reticulum; plasma membrane; azurophil granule membrane;
Biological process	phospholipid biosynthetic process; retina development in camera-type eye; lipid metabolism; phosphatidylglycerol acyl-chain remodeling; positive regulation of protein catabolic process; phosphatidic acid biosynthetic process; metabolism; surfactant homeostasis; negative regulation of phosphatidylcholine biosynthetic process; phosphatidylcholine acyl-chain remodeling; phospholipid metabolic process; phosphatidylcholine biosynthetic process; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	79888
	210992
	ENSG00000275079; ENSG00000153395
	ENSMUSG00000021608
	Q8NF37
	Q3TFD2
	NM_024830
	NM_145376; NM_001368681; NM_001368682
	NP_079106
	NP_663351; NP_001355610; NP_001355611
	Wikidata
View/Edit Human	View/Edit Mouse

Lysophosphatidylcholine acyltransferase 1 is a protein in humans that is encoded by the LPCAT1 gene.

Lysophosphatidylcholine (LPC) acyltransferase (LPCAT; EC 2.3.1.23) catalyzes the conversion of LPC to phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis.