Lecithin retinol acyltransferase

LRAT
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4Q95
Identifiers
Aliases	LRAT, LCA14, lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase), lecithin retinol acyltransferase
External IDs	OMIM: 604863; MGI: 1891259; HomoloGene: 3483; GeneCards: LRAT; OMA:LRAT - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	154,753,120 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	82,811,280 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; testicle; ; gonad; ; gallbladder; ; jejunal mucosa; ; C1 segment; ; duodenum; ; right lobe of liver; ; muscle layer of sigmoid colon; ; tibial nerve;
	Top expressed in
	retinal pigment epithelium; ; median eminence; ; arcuate nucleus; ; epithelium of small intestine; ; right lung; ; right lung lobe; ; Paneth cell; ; ciliary body; ; duodenum; ; migratory enteric neural crest cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	acyltransferase activity; retinol binding; O-acyltransferase activity; transferase activity; retinoic acid binding; lecithin:11-cis retinol acyltransferase activity; O-palmitoyltransferase activity; phosphatidylcholine-retinol O-acyltransferase activity;
Cellular component	endoplasmic reticulum; cytoplasm; endosome; integral component of membrane; membrane; intracellular membrane-bounded organelle; endoplasmic reticulum membrane; multivesicular body; rough endoplasmic reticulum; perinuclear region of cytoplasm;
Biological process	vitamin A metabolic process; visual perception; retinoid metabolic process; response to stimulus; positive regulation of lipid transport; cellular response to leukemia inhibitory factor; retinol metabolic process; response to retinoic acid; response to vitamin A; response to bacterium;
	Sources:Amigo / QuickGO
Orthologs
	9227
	79235
	ENSG00000121207
	ENSMUSG00000028003
	O95237
	Q9JI60
	NM_001301645; NM_004744
	NM_023624
	NP_001288574; NP_004735
	NP_076113
	Wikidata
View/Edit Human	View/Edit Mouse

Lecithin retinol acyltransferase is an enzyme that in humans is encoded by the LRAT gene.