LRRC7

LRRC7
Identifiers
Aliases	LRRC7, DENSIN, leucine rich repeat containing 7
External IDs	OMIM: 614453; MGI: 2676665; HomoloGene: 10817; GeneCards: LRRC7; OMA:LRRC7 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	70,151,945 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	158,267,858 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; primary visual cortex; ; nucleus accumbens; ; middle temporal gyrus; ; Brodmann area 9; ; ganglionic eminence; ; caudate nucleus; ; putamen; ; Brodmann area 46; ; hippocampus proper;
	Top expressed in
	medial geniculate nucleus; ; medial dorsal nucleus; ; lateral geniculate nucleus; ; olfactory tubercle; ; Rostral migratory stream; ; dentate gyrus of hippocampal formation granule cell; ; piriform cortex; ; primary motor cortex; ; Region I of hippocampus proper; ; cingulate gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; ionotropic glutamate receptor binding;
Cellular component	cell junction; postsynaptic membrane; synapse; membrane; postsynaptic density; extracellular region; specific granule lumen; cytoplasm; plasma membrane; neuron projection; cell-cell junction; ionotropic glutamate receptor complex; basolateral plasma membrane; axon initial segment; cytosol;
Biological process	neutrophil degranulation; signal transduction; positive regulation of neuron projection development; receptor clustering; establishment or maintenance of epithelial cell apical/basal polarity; receptor localization to synapse; cell-cell adhesion; neurotransmitter receptor transport, endosome to postsynaptic membrane; neurotransmitter receptor transport postsynaptic membrane to endosome; MAPK cascade; regulation of NMDA receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	57554
	242274
	ENSG00000033122
	ENSMUSG00000028176
	Q96NW7
	Q80TE7
NM_020794; NM_001330635; NM_001350216; NM_001366836; NM_001366837;
	NM_001366838; NM_001366839; NM_001366840; NM_001366841; NM_001366842; NM_001370785
	NM_001081358; NM_001291452; NM_001291453; NM_001370781; NM_001370782
NP_001317564; NP_001337145; NP_001353765; NP_001353766; NP_001353767;
	NP_001353768; NP_001353769; NP_001353770; NP_001353771; NP_001357714
	NP_001074827; NP_001278381; NP_001278382; NP_001357710; NP_001357711
	Wikidata
View/Edit Human	View/Edit Mouse

Leucine rich repeat containing 7 also known as LRRC7, Densin-180, or LAP1 is a protein which in humans is encoded by the LRRC7 gene.