LRRFIP1

LRRFIP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4H22
Identifiers
Aliases	LRRFIP1, FLAP-1, FLAP1, FLIIAP1, GCF-2, GCF2, HUFI-1, TRIP, leucine rich repeat (in FLII) interacting protein 1, LRR binding FLII interacting protein 1
External IDs	OMIM: 603256; MGI: 1342770; HomoloGene: 48301; GeneCards: LRRFIP1; OMA:LRRFIP1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	237,813,682 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	91,128,944 bp
RNA expression pattern
	Top expressed in
	renal medulla; ; endothelial cell; ; cardia; ; nipple; ; pylorus; ; visceral pleura; ; superior surface of tongue; ; buccal mucosa cell; ; mucosa of pharynx; ; pericardium;
	Top expressed in
	secondary oocyte; ; zygote; ; endothelial cell of lymphatic vessel; ; conjunctival fornix; ; granulocyte; ; primary oocyte; ; urothelium; ; hair follicle; ; transitional epithelium of urinary bladder; ; lacrimal gland;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; double-stranded RNA binding; protein binding; protein homodimerization activity; cadherin binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	plasma membrane; cytoskeleton; nucleus; cytoplasm; cytosol;
Biological process	regulation of transcription by RNA polymerase II; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; positive regulation of type I interferon production; transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; positive regulation of NF-kappaB transcription factor activity;
	Sources:Amigo / QuickGO
Orthologs
	9208
	16978
	ENSG00000124831
	ENSMUSG00000026305
	Q32MZ4
	Q3UZ39
	NM_001137550; NM_001137551; NM_001137552; NM_001137553; NM_004735
	NM_001111311; NM_001111312; NM_008515; NM_001310732
	NP_001131022; NP_001131023; NP_001131024; NP_001131025; NP_004726
	NP_001104781; NP_001104782; NP_001297661; NP_032541
	Wikidata
View/Edit Human	View/Edit Mouse

Leucine-rich repeat flightless-interacting protein 1 is a protein that in humans is encoded by the LRRFIP1 gene.