LSM8

LSM8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3JCR
Identifiers
Aliases	LSM8, NAA38, LSM8 homolog, U6 small nuclear RNA associated
External IDs	OMIM: 607288; MGI: 1923772; HomoloGene: 9419; GeneCards: LSM8; OMA:LSM8 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	118,204,035 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	18,855,750 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; epithelium of colon; ; right ventricle; ; ventricular zone; ; monocyte; ; bone marrow; ; bone marrow cells; ; skin of thigh; ; granulocyte; ; oocyte;
	Top expressed in
	primitive streak; ; abdominal wall; ; medial ganglionic eminence; ; hair follicle; ; vas deferens; ; embryo; ; migratory enteric neural crest cell; ; mandibular prominence; ; Gonadal ridge; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; U6 snRNA binding; RNA binding;
Cellular component	spliceosomal complex; nucleus; nucleoplasm; U4/U6 x U5 tri-snRNP complex; U6 snRNP; precatalytic spliceosome; U2-type precatalytic spliceosome; Lsm2-8 complex;
Biological process	mRNA processing; RNA splicing; mRNA splicing, via spliceosome; RNA metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	51691
	76522
	ENSG00000128534
	ENSMUSG00000044155
	O95777
	Q6ZWM4
	NM_016200
	NM_133939
	NP_057284
	NP_598700
	Wikidata
View/Edit Human	View/Edit Mouse

U6 snRNA-associated Sm-like protein LSm8 is a protein that in humans is encoded by the LSM8 gene.

This gene is a member of the LSm family and encodes a protein with a closed barrel shape, made up of five anti-parallel beta strands and an alpha helix. The protein partners with six paralogs to form a heteroheptameric ring which transiently binds RNAs and is involved in the general maturation of RNA in the nucleus.