Leukocyte receptor tyrosine kinase

LTK
Identifiers
Aliases	LTK, TYK1, Leukocyte receptor tyrosine kinase
External IDs	OMIM: 151520; MGI: 96840; HomoloGene: 130502; GeneCards: LTK; OMA:LTK - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	41,513,887 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	119,590,912 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; right lung; ; parotid gland; ; testicle; ; upper lobe of left lung; ; duodenum; ; rectum; ; jejunal mucosa; ; olfactory zone of nasal mucosa; ; body of stomach;
	Top expressed in
	perirhinal cortex; ; entorhinal cortex; ; CA3 field; ; Ileal epithelium; ; lactiferous gland; ; embryo; ; visual cortex; ; primary visual cortex; ; olfactory epithelium; ; superior frontal gyrus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; protein kinase activity; nucleotide binding; kinase activity; transmembrane receptor protein tyrosine kinase activity; protein tyrosine kinase activity; ATP binding; protein binding; receptor tyrosine kinase; transmembrane signaling receptor activity;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; intracellular anatomical structure; cytoplasm; receptor complex;
Biological process	cellular response to retinoic acid; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of cardiac muscle cell apoptotic process; negative regulation of apoptotic process; protein phosphorylation; positive regulation of neuron projection development; phosphatidylinositol 3-kinase signaling; cell population proliferation; peptidyl-tyrosine phosphorylation; signal transduction; negative regulation of signal transduction; cell differentiation; positive regulation of ERK1 and ERK2 cascade; regulation of neuron differentiation;
	Sources:Amigo / QuickGO
Orthologs
	4058
	17005
	ENSG00000062524
	ENSMUSG00000027297
	P29376
	P08923
	NM_001135685; NM_002344; NM_206961
	NM_008523; NM_203345; NM_206941; NM_206942
	NP_001129157; NP_002335; NP_996844
	NP_032549; NP_976220; NP_996824; NP_996825
	Wikidata
View/Edit Human	View/Edit Mouse

Leukocyte receptor tyrosine kinase is an enzyme that in humans is encoded by the LTK gene.