Lumican

LUM
Identifiers
Aliases	LUM, LDC, SLRR2D, lumican
External IDs	OMIM: 600616; MGI: 109347; HomoloGene: 37614; GeneCards: LUM; OMA:LUM - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	91,111,494 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	97,408,565 bp
RNA expression pattern
	Top expressed in
	gallbladder; ; mucosa of paranasal sinus; ; Achilles tendon; ; synovial joint; ; tibia; ; visceral pleura; ; superficial temporal artery; ; lactiferous duct; ; tendon of biceps brachii; ; vena cava;
	Top expressed in
	calvaria; ; molar; ; body of femur; ; dermis; ; umbilical cord; ; efferent ductule; ; vas deferens; ; semi-lunar valve; ; ankle; ; sciatic nerve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	collagen binding; extracellular matrix structural constituent; protein binding; extracellular matrix structural constituent conferring compression resistance;
Cellular component	extracellular matrix; fibrillar collagen trimer; lysosomal lumen; Golgi lumen; extracellular exosome; extracellular space; extracellular region; collagen-containing extracellular matrix;
Biological process	response to organic cyclic compound; axonogenesis; collagen fibril organization; extracellular matrix organization; positive regulation of transforming growth factor beta1 production; cartilage development; keratan sulfate catabolic process; response to growth factor; keratan sulfate biosynthetic process; positive regulation of transcription by RNA polymerase II; visual perception;
	Sources:Amigo / QuickGO
Orthologs
	4060
	17022
	ENSG00000139329
	ENSMUSG00000036446
	P51884
	P51885
	NM_002345
	NM_008524
	NP_002336
	NP_032550
	Wikidata
View/Edit Human	View/Edit Mouse

Lumican, also known as LUM, is an extracellular matrix protein that, in humans, is encoded by the LUM gene on chromosome 12.