LYPD6B

LYPD6B
Identifiers
Aliases	LYPD6B, CT116, LYPD7, LY6/PLAUR domain containing 6B
External IDs	MGI: 1919147; HomoloGene: 12419; GeneCards: LYPD6B; OMA:LYPD6B - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	149,215,262 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	49,838,861 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; right uterine tube; ; skin of leg; ; gallbladder; ; nasal epithelium; ; right testis; ; left testis; ; olfactory zone of nasal mucosa; ; palpebral conjunctiva; ; mucosa of paranasal sinus;
	Top expressed in
	medullary collecting duct; ; epithelium of stomach; ; molar; ; skin of abdomen; ; hair follicle; ; anterior horn of spinal cord; ; otolith organ; ; utricle; ; lumbar subsegment of spinal cord; ; urothelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	acetylcholine receptor regulator activity;
Cellular component	membrane; anchored component of membrane; extracellular region; plasma membrane;
Biological process	regulation of neurotransmitter receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	130576
	71897
	ENSG00000150556
	ENSMUSG00000026765
	Q8NI32
	Q9D7F2
NM_177964; NM_001317002; NM_001317003; NM_001317004; NM_001317005;
	NM_001317006
NM_027990; NM_001379381; NM_001379382; NM_001379383; NM_001379384;
	NM_001379385; NM_001379386; NM_001379387
NP_001303931; NP_001303932; NP_001303933; NP_001303934; NP_001303935;
	NP_808879
NP_082266; NP_001366310; NP_001366311; NP_001366312; NP_001366313;
	NP_001366314; NP_001366315; NP_001366316
	Wikidata
View/Edit Human	View/Edit Mouse

LY6/PLAUR Domain Containing 6B, also known under the name Cancer/Testis Antigen 116 (CTA116) and LYPD7 is encoded by the LYPD6B gene. LYPD6B is a member of the lymphocyte antigen 6 (LY6) protein family. It is expressed in the testis, lungs, stomach, prostate and in the nervous system where it acts as a modulator of nicotinic acetylcholine receptor (nAChRs) activity.