Transmembrane protein 251

TMEM251
Identifiers
Aliases	TMEM251, C14orf109, transmembrane protein 251, DMAN
External IDs	MGI: 2443862; HomoloGene: 100948; GeneCards: TMEM251; OMA:TMEM251 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	93,188,463 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	102,713,820 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; mucosa of transverse colon; ; rectum; ; endometrium; ; monocyte; ; human kidney; ; ventricular zone; ; apex of heart; ; gastrocnemius muscle; ; right adrenal cortex;
	Top expressed in
	peripheral nervous system; ; superior cervical ganglion; ; spinal ganglia; ; left ventricle; ; granulocyte; ; interventricular septum; ; primary oocyte; ; proximal tubule; ; right kidney; ; upper arm;
	More reference expression data
	n/a
Orthologs
	26175
	320351
	ENSG00000275947; ENSG00000153485
	ENSMUSG00000046675
	Q8N6I4
	Q8BH26
	NM_015676; NM_001098621
	NM_177140; NM_001324515
	NP_001092091; NP_056491
	NP_001311444; NP_796114
	Wikidata
View/Edit Human	View/Edit Mouse

Transmembrane protein 251, also known as C14orf109 or UPF0694, is a protein that in humans is encoded by the TMEM251 gene. One notable feature of this protein is the presence of proline residues on one of its predicted transmembrane domains, which is a determinant of the intramitochondrial sorting of inner membrane proteins.