LZTR1

LZTR1
Identifiers
Aliases	LZTR1, BTBD29, LZTR-1, SWNTS2, NS10, leucine-zipper-like transcription regulator 1, leucine zipper like transcription regulator 1, NS2
External IDs	OMIM: 600574; MGI: 1914113; HomoloGene: 4925; GeneCards: LZTR1; OMA:LZTR1 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	20,999,032 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	17,344,197 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; pituitary gland; ; anterior pituitary; ; right hemisphere of cerebellum; ; stromal cell of endometrium; ; granulocyte; ; body of uterus; ; right ovary; ; myometrium; ; left ovary;
	Top expressed in
	external carotid artery; ; internal carotid artery; ; otic vesicle; ; dentate gyrus of hippocampal formation granule cell; ; subiculum; ; fossa; ; substantia nigra; ; trigeminal ganglion; ; condyle; ; primary motor cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity;
Cellular component	Golgi apparatus;
Biological process	anatomical structure morphogenesis; regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	8216
	66863
	ENSG00000099949
	ENSMUSG00000022761
	Q8N653
	Q9CQ33
	NM_006767
	NM_025808; NM_001331226; NM_001331227
	NP_006758
	NP_001318155; NP_001318156; NP_080084
	Wikidata
View/Edit Human	View/Edit Mouse

Leucine-zipper-like transcriptional regulator 1 is a protein that in humans is encoded by the LZTR1 gene.

The LZTR1 gene provides instructions for making a protein among the class of the superfamily broad complex, tamtrack & brick-a-bac / poxvirus and zinc finger (BTB/POZ). The superfamily of proteins has a wide range of functions including chromatin condensation during conformation of the cell cycle. Other names associated with the LZTR gene are: BTBD29, LZTR-1, NS10, NS2, SWNTS2. This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex.