LZTS1

LZTS1
Identifiers
Aliases	LZTS1, F37, FEZ1, leucine zipper, putative tumor suppressor 1, leucine zipper tumor suppressor 1
External IDs	OMIM: 606551; MGI: 2684762; HomoloGene: 10873; GeneCards: LZTS1; OMA:LZTS1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	20,303,963 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	69,636,877 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; nucleus accumbens; ; Brodmann area 23; ; primary visual cortex; ; right frontal lobe; ; caudate nucleus; ; Amygdala; ; prefrontal cortex; ; putamen; ; dorsolateral prefrontal cortex;
	Top expressed in
	olfactory tubercle; ; piriform cortex; ; dorsal striatum; ; Rostral migratory stream; ; Region I of hippocampus proper; ; lumbar spinal ganglion; ; lateral septal nucleus; ; superior frontal gyrus; ; nucleus accumbens; ; primary motor cortex;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; protein binding; microtubule binding;
Cellular component	cytoplasm; postsynaptic membrane; cell projection; membrane; postsynaptic density; plasma membrane; dendritic spine; synapse; cell junction; apical plasma membrane; neuron projection; dendritic shaft; cell body;
Biological process	negative regulation of macroautophagy; transcription, DNA-templated; cell cycle; regulation of transcription, DNA-templated; mitotic cell cycle phase transition; regulation of synaptic plasticity; regulation of dendrite morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	11178
	211134
	ENSG00000061337
	ENSMUSG00000036306
	Q9Y250
	P60853
	NM_021020; NM_001362884
	NM_199364; NM_001370971
	NP_066300; NP_001349813
	NP_955396; NP_001357900
	Wikidata
View/Edit Human	View/Edit Mouse

Leucine zipper putative tumor suppressor 1 is a protein that, in humans, is encoded by the LZTS1 gene.

In melanocytic cells LZTS1 gene expression may be regulated by MITF.