Landau–Kleffner syndrome

Landau–Kleffner syndrome
Other namesInfantile acquired aphasia, acquired epileptic aphasia, aphasia with convulsive disorder
Landau–Kleffner syndrome is characterized by aphasia and an abnormal EEG
SpecialtyNeurology, psychiatry 
SymptomsAphasia, inattention, hyperactivity, aggression, anxiety, seizures
Usual onsetAges 3 to 7
DurationLifelong
TreatmentSpeech therapy, medication
MedicationAnticonvulsants, corticosteroids
PrognosisVariable

Landau–Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare neurological syndrome that develops during childhood.

It is named after William Landau and Frank Kleffner, who characterized it in 1957 with a diagnosis of six children.