Leucine carboxyl methyltransferase 1

LCMT1
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	3IEI, 3O7W, 3P71
Identifiers
Aliases	LCMT1, LCMT, PPMT1, CGI-68, leucine carboxyl methyltransferase 1
External IDs	OMIM: 610286; MGI: 1353593; HomoloGene: 41123; GeneCards: LCMT1; OMA:LCMT1 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	25,178,231 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	123,029,581 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; body of pancreas; ; prefrontal cortex; ; oocyte; ; nucleus accumbens; ; right frontal lobe; ; gonad; ; Pons; ; Brodmann area 23; ; anterior cingulate cortex;
	Top expressed in
	lacrimal gland; ; dentate gyrus of hippocampal formation granule cell; ; Region I of hippocampus proper; ; ventromedial nucleus; ; medial ganglionic eminence; ; anterior amygdaloid area; ; nucleus accumbens; ; nucleus of stria terminalis; ; dorsomedial hypothalamic nucleus; ; superior frontal gyrus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; protein methyltransferase activity; S-adenosylmethionine-dependent methyltransferase activity; transferase activity; protein binding; protein C-terminal carboxyl O-methyltransferase activity; protein C-terminal leucine carboxyl O-methyltransferase activity;
Cellular component	cytosol; nucleoplasm;
Biological process	regulation of mitotic cell cycle spindle assembly checkpoint; methylation; C-terminal protein methylation; regulation of glucose metabolic process; regulation of apoptotic process; negative regulation of protein-containing complex assembly; protein methylation; G2/M transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	51451
	30949
	ENSG00000205629
	ENSMUSG00000030763
	Q9UIC8
	n/a
	NM_001032391; NM_016309; NM_016015
	NM_025304; NM_001355050
	NP_001027563; NP_057393
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Leucine carboxyl methyltransferase 1 is an enzyme that in humans is encoded by the LCMT1 gene.