Leuckart reaction

Leuckart reaction
Named after Rudolf Leuckart
Reaction type Substitution reaction
Identifiers
RSC ontology ID RXNO:0000101

The Leuckart reaction is the chemical reaction that converts aldehydes or ketones to amines. The reaction is an example of reductive amination. The reaction, named after Rudolf Leuckart, uses either ammonium formate or formamide as the nitrogen donor and reducing agent. It requires high temperatures, usually between 120 and 130 °C; for the formamide variant, the temperature can be greater than 165 °C.

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