Plant lipid transfer proteins

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary
PDB	PDB: 1UVB PDB: 1afh PDB: 1b1u PDB: 1be2 PDB: 1bea PDB: 1bfa PDB: 1bip PDB: 1bwo PDB: 1cz2 PDB: 1fk0 PDB: 1fk1

Plant lipid transfer protein / bifunctional inhibitor / seed storage protein, 4-helical domain
Plant lipid transfer protein / bifunctional inhibitor / seed storage protein, 4-helical domain
	Oryza sativa Lipid Transfer Protein 1 bound to palmitic acid (black). Positive charge in blue; negative charge in red (PDB: 1UVB).
Identifiers
Symbol	LTP/seed_store/tryp_amyl_inhib
Pfam	PF00234
Pfam clan	CL0482
InterPro	IPR016140
SMART	SM00499
CATH	1UVB
SCOP2	1UVB / SCOPe / SUPFAM
CDD	cd00010
Pfam
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary
PDB	PDB: 1UVB PDB: 1afh PDB: 1b1u PDB: 1be2 PDB: 1bea PDB: 1bfa PDB: 1bip PDB: 1bwo PDB: 1cz2 PDB: 1fk0 PDB: 1fk1
	Also Pfam PF13016, PF14368; see the Pfam clan relationships.

Plant lipid transfer proteins, also known as plant LTPs or PLTPs, are a group of highly-conserved proteins of about 7-9kDa found in higher plant tissues. As its name implies, lipid transfer proteins facilitate the shuttling of phospholipids and other fatty acid groups between cell membranes. LTPs are divided into two structurally related subfamilies according to their molecular masses: LTP1s (9 kDa) and LTP2s (7 kDa). Various LTPs bind a wide range of ligands, including fatty acids with a C₁₀–C₁₈ chain length, acyl derivatives of coenzyme A, phospho- and galactolipids, prostaglandin B₂, sterols, molecules of organic solvents, and some drugs.

The LTP domain is also found in seed storage proteins (including 2S albumin, gliadin, and glutelin) and bifunctional trypsin/alpha-amylase inhibitors. These proteins share the same superhelical, disulfide-stabilised four-helix bundle containing an internal cavity.

There is no sequence similarity between animal and plant LTPs. In animals, cholesteryl ester transfer protein, also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins.