Lipoxin

Lipoxins A₄ and B₄
	Lipoxin A4
	Lipoxin B4
Names
	Preferred IUPAC name A4: (5S,6R,7E,9E,11Z,13E,15S)-5,6,15-Trihydroxyicosa-7,9,11,13-tetraenoic acid; B4: (5S,6E,8Z,10E,12E,14R,15S)-5,14,15-Trihydroxyicosa-6,8,10,12-tetraenoic acid
	Other names LXA4 and LXB4
Identifiers
CAS Number	89663-86-5 A4 ; 98049-69-5 B4 ;
3D model (JSmol)	A4: Interactive image; B4: Interactive image;
ChEBI	CHEBI:6498 ; CHEBI:6499 ;
ChemSpider	4444429 A4 ; 4444430 B4 ;
IUPHAR/BPS	1034 A4; 5216 B4;
PubChem CID	5280914 A4; 5280915 B4;
CompTox Dashboard (EPA)	DTXSID701318336 ;
	InChI InChI=1S/C20H32O5/c1-2-3-8-14-18(22)19(23)15-10-7-5-4-6-9-12-17(21)13-11-16-20(24)25/h4-7,9-10,12,15,17-19,21-23H,2-3,8,11,13-14,16H2,1H3,(H,24,25)/b6-4-,7-5+,12-9+,15-10+/t17-,18+,19-/m1/s1 Key: UXVRTOKOJOMENI-WLPVFMORSA-N ; A4: InChI=1S/C20H32O5/c1-2-3-8-12-17(21)13-9-6-4-5-7-10-14-18(22)19(23)15-11-16-20(24)25/h4-7,9-10,13-14,17-19,21-23H,2-3,8,11-12,15-16H2,1H3,(H,24,25)/b6-4-,7-5+,13-9+,14-10+/t17-,18+,19-/m0/s1 Key: IXAQOQZEOGMIQS-SSQFXEBMSA-N; B4: InChI=1S/C20H32O5/c1-2-3-8-14-18(22)19(23)15-10-7-5-4-6-9-12-17(21)13-11-16-20(24)25/h4-7,9-10,12,15,17-19,21-23H,2-3,8,11,13-14,16H2,1H3,(H,24,25)/b6-4-,7-5+,12-9+,15-10+/t17-,18+,19-/m1/s1 Key: UXVRTOKOJOMENI-WLPVFMORSA-N;
	SMILES A4: CCCCC[C@H](O)C=C\C=C/C=CC=CC(O)C(O)CCCC(O)=O; B4: O=C(O)CCC[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCCC;
Properties
Chemical formula	C20H32O5
Molar mass	352.46508 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

A lipoxin (LX or Lx), an acronym for lipoxygenase interaction product, is a bioactive autacoid metabolite of arachidonic acid made by various cell types. They are categorized as nonclassic eicosanoids and members of the specialized pro-resolving mediator (SPM) family of polyunsaturated fatty acid (PUFA) metabolites. Like other SPMs, LXs form during an inflammatory response and act to resolve it. The first lipoxins identified were lipoxin A₄ (LXA₄) and lipoxin B₄ (LXB₄), followed by their respective epimers, the epi-lipoxins 15-epi-LXA₄ and 15-epi-LXB₄.

Names
Lipoxin A₄
Lipoxin B₄
Preferred IUPAC name A4: (5S,6R,7E,9E,11Z,13E,15S)-5,6,15-Trihydroxyicosa-7,9,11,13-tetraenoic acid B4: (5S,6E,8Z,10E,12E,14R,15S)-5,14,15-Trihydroxyicosa-6,8,10,12-tetraenoic acid
Other names LXA4 and LXB4
Identifiers
CAS Number	89663-86-5 A4^Y 98049-69-5 B4^Y
3D model (JSmol)	A4: Interactive image B4: Interactive image
ChEBI	CHEBI:6498^Y CHEBI:6499^Y
ChemSpider	4444429 A4^Y 4444430 B4^Y
IUPHAR/BPS	1034 A4 5216 B4
PubChem CID	5280914 A4 5280915 B4
CompTox Dashboard (EPA)	DTXSID701318336
InChI InChI=1S/C20H32O5/c1-2-3-8-14-18(22)19(23)15-10-7-5-4-6-9-12-17(21)13-11-16-20(24)25/h4-7,9-10,12,15,17-19,21-23H,2-3,8,11,13-14,16H2,1H3,(H,24,25)/b6-4-,7-5+,12-9+,15-10+/t17-,18+,19-/m1/s1^Y Key: UXVRTOKOJOMENI-WLPVFMORSA-N^Y A4: InChI=1S/C20H32O5/c1-2-3-8-12-17(21)13-9-6-4-5-7-10-14-18(22)19(23)15-11-16-20(24)25/h4-7,9-10,13-14,17-19,21-23H,2-3,8,11-12,15-16H2,1H3,(H,24,25)/b6-4-,7-5+,13-9+,14-10+/t17-,18+,19-/m0/s1 Key: IXAQOQZEOGMIQS-SSQFXEBMSA-N B4: InChI=1S/C20H32O5/c1-2-3-8-14-18(22)19(23)15-10-7-5-4-6-9-12-17(21)13-11-16-20(24)25/h4-7,9-10,12,15,17-19,21-23H,2-3,8,11,13-14,16H2,1H3,(H,24,25)/b6-4-,7-5+,12-9+,15-10+/t17-,18+,19-/m1/s1 Key: UXVRTOKOJOMENI-WLPVFMORSA-N
SMILES A4: CCCCC[C@H](O)C=C\C=C/C=CC=CC(O)C(O)CCCC(O)=O B4: O=C(O)CCC[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCCC
Properties
Chemical formula	C₂₀H₃₂O₅
Molar mass	352.46508 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is ^YN ?) Infobox references