Loprazolam

Loprazolam
Clinical data
Trade namesDormonoct, Havlane, Sonin, Somnovit, others
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • D
Routes of
administration
Oral
ATC code
Legal status
Legal status
Pharmacokinetic data
MetabolismHepatic
Elimination half-life6–12 hours
ExcretionRenal
Identifiers
  • (2Z)-6-(2-Chlorophenyl)-2-[(4-methyl-1-piperazinyl)methylene]-8-nitro-2,4-dihydro-1H-imidazo[1,2-a][1,4]benzodiazepin-1-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.293.781
Chemical and physical data
FormulaC23H21ClN6O3
Molar mass464.91 g·mol−1
3D model (JSmol)
  • [O-][N+](=O)c1cc4c(cc1)N/2C(=O)C(\N=C\2C/N=C4/c3ccccc3Cl)=C\N5CCN(C)CC5
  • InChI=1S/C23H21ClN6O3/c1-27-8-10-28(11-9-27)14-19-23(31)29-20-7-6-15(30(32)33)12-17(20)22(25-13-21(29)26-19)16-4-2-3-5-18(16)24/h2-7,12,14H,8-11,13H2,1H3/b19-14- Y
  • Key:UTEFBSAVJNEPTR-RGEXLXHISA-N Y
 NY (what is this?)  (verify)

Loprazolam (triazulenone) marketed under many brand names is a benzodiazepine medication. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. It is licensed and marketed for the short-term treatment of moderately-severe insomnia.

It was patented in 1975 and came into medical use in 1983.