H2AFY2

MACROH2A2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XD7
Identifiers
Aliases	MACROH2A2, macroH2A2, H2A histone family member Y2, H2AFY2, macroH2A.2 histone
External IDs	OMIM: 616141; MGI: 3037658; HomoloGene: 10246; GeneCards: MACROH2A2; OMA:MACROH2A2 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	70,112,282 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	61,619,926 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; epithelium of colon; ; gingival epithelium; ; cerebellar vermis; ; pancreatic epithelial cell; ; islet of Langerhans; ; epithelium of esophagus; ; hair follicle; ; cerebellar hemisphere;
	Top expressed in
	genital tubercle; ; tail of embryo; ; neural tube; ; ventricular zone; ; maxillary prominence; ; ganglionic eminence; ; mandibular prominence; ; medial ganglionic eminence; ; otic placode; ; abdominal wall;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein heterodimerization activity; chromatin DNA binding;
Cellular component	ESC/E(Z) complex; nucleoplasm; chromosome; nucleosome; chromatin; extracellular exosome; Barr body; nucleus;
Biological process	nucleosome assembly; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I; positive regulation of keratinocyte differentiation; dosage compensation; negative regulation of transcription by RNA polymerase II; establishment of protein localization to chromatin; brain development; negative regulation of gene expression, epigenetic; regulation of cell growth; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	55506
	404634
	ENSG00000099284
	ENSMUSG00000020086
	Q9P0M6
	Q8CCK0
	NM_018649
	NM_207000
	NP_061119
	NP_996883
	Wikidata
View/Edit Human	View/Edit Mouse

Core histone macro-H2A.2 is a protein that in humans is encoded by the H2AFY2 gene.