MAFB (gene)

MAFB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2WT7, 2WTY, 4AUW
Identifiers
Aliases	MAFB, KRML, MCTO, MAF bZIP transcription factor B, DURS3
External IDs	OMIM: 608968; MGI: 104555; HomoloGene: 31315; GeneCards: MAFB; OMA:MAFB - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	40,689,236 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	160,208,985 bp
RNA expression pattern
	Top expressed in
	glomerulus; ; skin of hip; ; gums; ; metanephric glomerulus; ; gingival epithelium; ; synovial membrane; ; human penis; ; synovial joint; ; nipple; ; skin of arm;
	Top expressed in
	molar; ; stroma of bone marrow; ; temporal muscle; ; glomerulus; ; sternocleidomastoid muscle; ; lip; ; skin of external ear; ; digastric muscle; ; left lobe of liver; ; muscle of thigh;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; transcription factor binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; protein homodimerization activity; protein heterodimerization activity; sequence-specific double-stranded DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding;
Cellular component	transcription regulator complex; nucleus;
Biological process	T cell differentiation in thymus; negative regulation of osteoclast differentiation; brain segmentation; thymus development; transcription by RNA polymerase II; respiratory gaseous exchange by respiratory system; segment specification; negative regulation of erythrocyte differentiation; nervous system development; transcription, DNA-templated; rhombomere 6 development; rhombomere 5 development; inner ear morphogenesis; sensory organ development; positive regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; abducens nerve formation; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	9935
	16658
	ENSG00000204103
	ENSMUSG00000074622
	Q9Y5Q3
	P54841
	NM_005461
	NM_010658
	NP_005452
	NP_034788
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor MafB also known as V-maf musculoaponeurotic fibrosarcoma oncogene homolog B is a protein that in humans is encoded by the MAFB gene. This gene maps to chromosome 20q11.2-q13.1, consists of a single exon and spans around 3 kb.