MAFK

MAFK
Identifiers
Aliases	MAFK, NFE2U, P18, MAF bZIP transcription factor K
External IDs	OMIM: 600197; MGI: 99951; HomoloGene: 1770; GeneCards: MAFK; OMA:MAFK - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	1,543,043 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	139,788,408 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; ascending aorta; ; popliteal artery; ; tibial arteries; ; right coronary artery; ; gastric mucosa; ; right lung; ; saphenous vein; ; muscle layer of sigmoid colon; ; left coronary artery;
	Top expressed in
	granulocyte; ; ascending aorta; ; muscle of thigh; ; aortic valve; ; fetal liver hematopoietic progenitor cell; ; right kidney; ; tibiofemoral joint; ; jejunum; ; yolk sac; ; digastric muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; transcription coregulator binding; transcription cis-regulatory region binding; protein binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RING-like zinc finger domain binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific;
Cellular component	nucleoplasm; nucleus;
Biological process	blood coagulation; regulation of transcription, DNA-templated; nervous system development; transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7975
	17135
	ENSG00000198517
	ENSMUSG00000018143
	O60675
	Q61827
	NM_002360
	NM_010757
	NP_002351
	NP_034887
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor MafK is a bZip Maf transcription factor protein that in humans is encoded by the MAFK gene.

MafK is one of the small Maf proteins, which are basic region and leucine zipper (bZIP)-type transcription factors. The HUGO Gene Nomenclature Committee-approved gene name of MAFK is “v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K”.