MAML1

MAML1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2F8X, 3NBN, 3V79
Identifiers
Aliases	MAML1, Mam-1, Mam1, mastermind like transcriptional coactivator 1
External IDs	OMIM: 605424; MGI: 1890504; HomoloGene: 8845; GeneCards: MAML1; OMA:MAML1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	179,777,283 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	50,183,138 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; ventricular zone; ; ganglionic eminence; ; gallbladder; ; right hemisphere of cerebellum; ; gastric mucosa; ; left uterine tube; ; rectum; ; left ovary; ; stromal cell of endometrium;
	Top expressed in
	left lung lobe; ; granulocyte; ; external carotid artery; ; internal carotid artery; ; endocardial cushion; ; vas deferens; ; genital tubercle; ; tail of embryo; ; abdominal wall; ; fossa;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptide antigen binding; transcription coactivator activity; protein binding; protein kinase binding;
Cellular component	nuclear speck; intracellular membrane-bounded organelle; nucleoplasm; nucleus; MAML1-RBP-Jkappa- ICN1 complex;
Biological process	Notch signaling pathway; positive regulation of myotube differentiation; atrioventricular node development; regulation of transcription, DNA-templated; positive regulation of muscle cell differentiation; atrioventricular node cell development; transcription, DNA-templated; protein phosphorylation; myoblast differentiation; transcription initiation from RNA polymerase II promoter; positive regulation of transcription by RNA polymerase II; positive regulation of transcription of Notch receptor target; positive regulation of Notch signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	9794
	103806
	ENSG00000161021
	ENSMUSG00000050567
	Q92585
	Q6T264
	NM_014757
	NM_175334
	NP_055572
	NP_780543; NP_001388483
	Wikidata
View/Edit Human	View/Edit Mouse

Mastermind-like protein 1 is a protein that in humans is encoded by the MAML1 gene.