MAN1B1

MAN1B1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1FMI, 1FO2, 1FO3, 1X9D
Identifiers
Aliases	MAN1B1, ERMAN1, MANA-ER, MRT15, ERManI, mannosidase alpha class 1B member 1
External IDs	OMIM: 604346; MGI: 2684954; HomoloGene: 5230; GeneCards: MAN1B1; OMA:MAN1B1 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	137,109,189 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	25,242,224 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; right uterine tube; ; skin of leg; ; anterior pituitary; ; apex of heart; ; skin of abdomen; ; right hemisphere of cerebellum; ; minor salivary glands; ; olfactory zone of nasal mucosa; ; right lobe of thyroid gland;
	Top expressed in
	spermatocyte; ; Ileal epithelium; ; spermatid; ; neural layer of retina; ; yolk sac; ; corneal stroma; ; granulocyte; ; ventricular zone; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; calcium ion binding; hydrolase activity, acting on glycosyl bonds; hydrolase activity; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; catalytic activity;
Cellular component	extracellular vesicle; integral component of membrane; Golgi apparatus; membrane; endoplasmic reticulum membrane; endoplasmic reticulum; endoplasmic reticulum quality control compartment; Golgi membrane;
Biological process	oligosaccharide metabolic process; metabolism; N-glycan processing; mannose trimming involved in glycoprotein ERAD pathway; protein alpha-1,2-demannosylation; protein glycosylation; ubiquitin-dependent ERAD pathway; trimming of terminal mannose on B branch; trimming of terminal mannose on C branch; trimming of first mannose on A branch; trimming of second mannose on A branch; endoplasmic reticulum mannose trimming;
	Sources:Amigo / QuickGO
Orthologs
	11253
	227619
	ENSG00000177239
	ENSMUSG00000036646
	Q9UKM7
	A2AJ15
	NM_016219
	NM_001029983
	NP_057303
	NP_001025154
	Wikidata
View/Edit Human	View/Edit Mouse

Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase is an enzyme that in humans is encoded by the MAN1B1 gene.