MAP3K13

MAP3K13
Identifiers
Aliases	MAP3K13, LZK, MEKK13, MLK, mitogen-activated protein kinase kinase kinase 13
External IDs	OMIM: 604915; MGI: 2444243; HomoloGene: 37958; GeneCards: MAP3K13; OMA:MAP3K13 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	185,489,094 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	21,752,189 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; caput epididymis; ; tail of epididymis; ; sperm; ; mucosa of paranasal sinus; ; lower lobe of lung; ; lactiferous duct; ; buccal mucosa cell; ; Pons; ; inferior ganglion of vagus nerve;
	Top expressed in
	ureter; ; ganglionic eminence; ; neural layer of retina; ; jejunum; ; Cerebellum; ; cerebellar cortex; ; colon; ; duodenum; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; protein homodimerization activity; identical protein binding; kinase activity; MAP kinase kinase kinase activity; protein serine/threonine kinase activity; protein kinase activity; ATP binding; protein kinase binding; metal ion binding; nucleotide binding; transferase activity; JUN kinase kinase kinase activity; IkappaB kinase complex binding; enzyme binding;
Cellular component	membrane; cytoplasm; IkappaB kinase complex;
Biological process	phosphorylation; JNK cascade; protein phosphorylation; protein autophosphorylation; positive regulation of NF-kappaB transcription factor activity; MAPK cascade; positive regulation of neuron maturation; peptidyl-serine phosphorylation; positive regulation of axon extension; positive regulation of neuron projection arborization; positive regulation of branching morphogenesis of a nerve;
	Sources:Amigo / QuickGO
Orthologs
	9175
	71751
	ENSG00000073803
	ENSMUSG00000033618
	O43283
	Q1HKZ5
	NM_001242314; NM_001242317; NM_004721
	NM_172821
	NP_001229243; NP_001229246; NP_004712
	NP_766409
	Wikidata
View/Edit Human	View/Edit Mouse

Mitogen-activated protein kinase kinase kinase 13 is an enzyme that in humans is encoded by the MAP3K13 gene.