MAP4K3

MAP4K3
Identifiers
Aliases	MAP4K3, GLK, MAPKKKK3, MEKKK 3, MEKKK3, RAB8IPL1, mitogen-activated protein kinase kinase kinase kinase 3
External IDs	OMIM: 604921; MGI: 2154405; HomoloGene: 2683; GeneCards: MAP4K3; OMA:MAP4K3 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	39,437,301 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	80,728,485 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; Achilles tendon; ; sural nerve; ; Skeletal muscle tissue of rectus abdominis; ; tibia; ; epithelium of colon; ; gastrocnemius muscle; ; biceps brachii; ; endometrium; ; jejunum;
	Top expressed in
	vestibular membrane of cochlear duct; ; epithelium of lens; ; Paneth cell; ; left lung lobe; ; retina; ; calvaria; ; Region I of hippocampus proper; ; fossa; ; vestibular sensory epithelium; ; cingulate gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; protein kinase activity; protein serine/threonine kinase activity; nucleotide binding; protein binding; ATP binding; kinase activity; MAP kinase kinase kinase kinase activity;
Cellular component	cytoplasm;
Biological process	response to tumor necrosis factor; protein phosphorylation; JNK cascade; intracellular signal transduction; response to UV; phosphorylation; regulation of mitotic cell cycle; regulation of apoptotic process; signal transduction; stress-activated protein kinase signaling cascade; activation of protein kinase activity;
	Sources:Amigo / QuickGO
Orthologs
	8491
	225028
	ENSG00000011566
	ENSMUSG00000024242
	Q8IVH8
	Q99JP0
	NM_001270425; NM_003618
	NM_001081357; NM_001290345; NM_001360278
	NP_001257354; NP_003609
	NP_001277274; NP_001347207
	Wikidata
View/Edit Human	View/Edit Mouse

Mitogen-activated protein kinase kinase kinase kinase 3 is a protein that in humans is encoded by the MAP4K3 gene.