MAPK7

MAPK7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2Q8Y, 4B99, 4IC7, 4IC8, 4ZSJ, 4ZSL, 5BYZ, 5BYY, 4ZSG
Identifiers
Aliases	MAPK7, BMK1, ERK4, ERK5, PRKM7, mitogen-activated protein kinase 7
External IDs	OMIM: 602521; MGI: 1346347; HomoloGene: 2060; GeneCards: MAPK7; OMA:MAPK7 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	19,383,544 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	61,494,406 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; stromal cell of endometrium; ; popliteal artery; ; tibial arteries; ; sural nerve; ; ventricular zone; ; ectocervix; ; granulocyte; ; right ovary; ; skin of leg;
	Top expressed in
	granulocyte; ; tail of embryo; ; genital tubercle; ; ventricular zone; ; neural tube; ; epiblast; ; ganglionic eminence; ; yolk sac; ; internal carotid artery; ; external carotid artery;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; mitogen-activated protein kinase binding; kinase activity; protein binding; ATP binding; protein serine/threonine kinase activity; MAP kinase activity;
Cellular component	cytoplasm; cytosol; PML body; nucleoplasm; nucleus;
Biological process	cellular response to transforming growth factor beta stimulus; negative regulation of endothelial cell apoptotic process; cell differentiation; phosphorylation; negative regulation of ERK5 cascade; cellular response to laminar fluid shear stress; positive regulation of transcription from RNA polymerase II promoter in response to stress; cellular response to growth factor stimulus; negative regulation of apoptotic process; regulation of angiogenesis; negative regulation of response to cytokine stimulus; protein phosphorylation; negative regulation of MAP kinase activity; peptidyl-serine phosphorylation; cell cycle; negative regulation of cyclic-nucleotide phosphodiesterase activity; negative regulation of heterotypic cell-cell adhesion; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of inflammatory response; cAMP-mediated signaling; signal transduction; positive regulation of transcription by RNA polymerase II; cellular response to hydrogen peroxide; MAPK cascade; axon guidance; negative regulation of calcineurin-NFAT signaling cascade; regulation of gene expression; intracellular signal transduction; cellular response to organic substance;
	Sources:Amigo / QuickGO
Orthologs
	5598
	23939
	ENSG00000166484
	ENSMUSG00000001034
	Q13164
	Q9WVS8
	NM_002749; NM_139032; NM_139033; NM_139034
NM_001291033; NM_001291034; NM_001291035; NM_001291036; NM_001291037;
	NM_011841; NM_001361989
	NP_002740; NP_620601; NP_620602; NP_620603
NP_001277962; NP_001277963; NP_001277964; NP_001277965; NP_001277966;
	NP_035971; NP_001348918
	Wikidata
View/Edit Human	View/Edit Mouse

Mitogen-activated protein kinase 7 also known as MAP kinase 7 is an enzyme that in humans is encoded by the MAPK7 gene.