MAPRE3

MAPRE3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WYO, 3CO1, 3JAK, 3JAL, 3JAR, 3TQ7
Identifiers
Aliases	MAPRE3, EB3, EBF3, EBF3-S, RP3, microtubule associated protein RP/EB family member 3
External IDs	OMIM: 605788; MGI: 2140967; HomoloGene: 56565; GeneCards: MAPRE3; OMA:MAPRE3 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	27,027,219 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	31,023,450 bp
RNA expression pattern
	Top expressed in
	Brodmann area 10; ; right hemisphere of cerebellum; ; right frontal lobe; ; right uterine tube; ; middle frontal gyrus; ; paraflocculus of cerebellum; ; frontal pole; ; cingulate gyrus; ; anterior cingulate cortex; ; anterior pituitary;
	Top expressed in
	neural layer of retina; ; superior frontal gyrus; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; muscle of thigh; ; perirhinal cortex; ; cerebellar cortex; ; CA3 field; ; spermatid; ; entorhinal cortex;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	microtubule binding; protein binding; identical protein binding; protein C-terminus binding; protein kinase binding; microtubule plus-end binding;
Cellular component	microtubule cytoskeleton; microtubule plus-end; perinuclear region of cytoplasm; cytoplasmic microtubule; midbody; microtubule; cytoskeleton; cytoplasm; microtubule organizing center; spindle midzone; mitotic spindle astral microtubule end;
Biological process	positive regulation of transcription, DNA-templated; cell cycle; positive regulation of microtubule plus-end binding; positive regulation of cyclin-dependent protein serine/threonine kinase activity; cell division; protein localization; regulation of microtubule polymerization or depolymerization; protein localization to microtubule; positive regulation of protein kinase activity; spindle assembly; protein localization to microtubule plus-end;
	Sources:Amigo / QuickGO
Orthologs
	22924
	100732
	ENSG00000084764
	ENSMUSG00000029166
	Q9UPY8
	Q6PER3
	NM_001303050; NM_012326
	NM_133350; NM_001310516
	NP_001289979; NP_036458
	NP_001297445; NP_579928
	Wikidata
View/Edit Human	View/Edit Mouse

Microtubule-associated protein RP/EB family member 3 is a protein that in humans is encoded by the MAPRE3 gene.

The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene.