MARK1

MARK1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2HAK, 3OSE
Identifiers
Aliases	MARK1, MARK, Par-1c, Par1c, microtubule affinity regulating kinase 1
External IDs	OMIM: 606511; MGI: 2664902; HomoloGene: 49552; GeneCards: MARK1; OMA:MARK1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	220,664,461 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	184,731,767 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; corpus epididymis; ; Pons; ; cerebellar vermis; ; Brodmann area 23; ; superior frontal gyrus; ; spinal ganglia; ; endothelial cell; ; primary visual cortex;
	Top expressed in
	trigeminal ganglion; ; motor neuron; ; barrel cortex; ; substantia nigra; ; fossa; ; external carotid artery; ; condyle; ; internal carotid artery; ; tunica media of zone of aorta; ; ascending aorta;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; phosphatidylserine binding; metal ion binding; kinase activity; phosphatidic acid binding; protein serine/threonine kinase activity; tau-protein kinase activity; phosphatidylinositol-4,5-bisphosphate binding; ATP binding; magnesium ion binding; lipid binding; protein binding; tau protein binding;
Cellular component	cytoplasm; membrane; microtubule cytoskeleton; plasma membrane; cytoskeleton; dendrite; cell projection;
Biological process	intracellular signal transduction; phosphorylation; neuron migration; Wnt signaling pathway; protein phosphorylation; cytoskeleton organization; establishment of cell polarity; microtubule cytoskeleton organization; regulation of neuron projection development; peptidyl-serine phosphorylation; regulation of dendrite development; establishment of mitochondrion localization;
	Sources:Amigo / QuickGO
Orthologs
	4139
	226778
	ENSG00000116141
	ENSMUSG00000026620
	Q9P0L2
	Q8VHJ5
	NM_001286124; NM_001286126; NM_001286128; NM_001286129; NM_018650
	NM_145515; NM_001378876
	NP_001273053; NP_001273055; NP_001273057; NP_001273058; NP_061120
	NP_663490; NP_001365805
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase MARK1 is an enzyme that in humans is encoded by the MARK1 gene.