MARK3

MARK3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2QNJ, 3FE3
Identifiers
Aliases	MARK3, CTAK1, KP78, PAR1A, Par-1a, microtubule affinity regulating kinase 3, VIPB
External IDs	OMIM: 602678; MGI: 1341865; HomoloGene: 55653; GeneCards: MARK3; OMA:MARK3 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	103,503,831 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	111,622,655 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; body of pancreas; ; apex of heart; ; right adrenal cortex; ; left uterine tube; ; right lung; ; right auricle of heart; ; left adrenal gland; ; left adrenal cortex;
	Top expressed in
	genital tubercle; ; tail of embryo; ; ventricular zone; ; spermatid; ; molar; ; right kidney; ; proximal tubule; ; Gonadal ridge; ; otic vesicle; ; ganglionic eminence;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; kinase activity; protein binding; ATP binding; protein serine/threonine kinase activity; tau protein binding; tau-protein kinase activity;
Cellular component	cytosol; membrane; extracellular exosome; plasma membrane; cytoplasm; dendrite; cell projection;
Biological process	phosphorylation; MAPK cascade; protein phosphorylation; microtubule cytoskeleton organization; establishment of cell polarity; negative regulation of hippo signaling; peptidyl-serine phosphorylation; positive regulation of protein binding; intracellular signal transduction; peptidyl-serine autophosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	4140
	17169
	ENSG00000075413
	ENSMUSG00000007411
	P27448
	Q03141
	NM_001128918; NM_001128919; NM_001128920; NM_001128921; NM_002376
	NM_021516; NM_022801; NM_001370744; NM_001370745
	NP_001122390; NP_001122391; NP_001122392; NP_001122393; NP_002367
	NP_067491; NP_073712; NP_001357673; NP_001357674
	Wikidata
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MAP/microtubule affinity-regulating kinase 3 is an enzyme that in humans is encoded by the MARK3 gene.