Matrilin-2

MATN2
Identifiers
Aliases	MATN2, matrilin 2
External IDs	OMIM: 602108; MGI: 109613; HomoloGene: 20538; GeneCards: MATN2; OMA:MATN2 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	98,036,724 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	34,436,419 bp
RNA expression pattern
	Top expressed in
	tibia; ; trigeminal ganglion; ; spinal ganglia; ; seminal vesicula; ; canal of the cervix; ; Achilles tendon; ; tail of epididymis; ; thyroid gland; ; right ovary; ; left lobe of thyroid gland;
	Top expressed in
	external carotid artery; ; efferent ductule; ; vas deferens; ; sciatic nerve; ; internal carotid artery; ; seminal vesicula; ; Gonadal ridge; ; tunica adventitia of aorta; ; cervix; ; decidua;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; protein binding; molecular function; extracellular matrix structural constituent;
Cellular component	extracellular region; basement membrane; extracellular matrix; extracellular space; collagen-containing extracellular matrix;
Biological process	glial cell migration; dendrite regeneration; axon guidance; neuron migration; response to axon injury; neuron projection development; biological process; growth plate cartilage chondrocyte morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	4147
	17181
	ENSG00000132561
	ENSMUSG00000022324
	O00339
	Q3TQ80
	NM_002380; NM_030583; NM_001317748
	NM_016762; NM_001358780
	NP_001304677; NP_002371; NP_085072
	NP_058042; NP_001345709
	Wikidata
View/Edit Human	View/Edit Mouse

Matrilin-2 is a matrilin protein that in humans is encoded by the MATN2 gene.

This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. The specific function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.