MBD3

MBD3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2MB7
Identifiers
Aliases	MBD3, methyl-CpG binding domain protein 3
External IDs	OMIM: 603573; MGI: 1333812; HomoloGene: 2917; GeneCards: MBD3; OMA:MBD3 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	1,592,865 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	80,235,384 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; right frontal lobe; ; cingulate gyrus; ; anterior cingulate cortex; ; Amygdala; ; mucosa of transverse colon; ; anterior pituitary; ; left uterine tube; ; right hemisphere of cerebellum; ; Brodmann area 10;
	Top expressed in
	ventricular zone; ; dentate gyrus of hippocampal formation granule cell; ; lip; ; yolk sac; ; muscle of thigh; ; superior frontal gyrus; ; choroid plexus of fourth ventricle; ; right kidney; ; epiblast; ; primary visual cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	methyl-CpG binding; DNA binding; nucleosomal DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; chromatin binding; histone deacetylase activity;
Cellular component	nucleus; nucleoplasm; heterochromatin; chromosome; NuRD complex; cytoplasm; chromatin; protein-containing complex;
Biological process	response to estradiol; tissue development; embryonic organ development; regulation of DNA methylation; in utero embryonic development; response to organic cyclic compound; regulation of transcription, DNA-templated; heart development; DNA methylation-dependent heterochromatin assembly; histone acetylation; negative regulation of transcription by RNA polymerase II; ageing; brain development; response to nutrient levels; transcription, DNA-templated; regulation of signal transduction by p53 class mediator; histone deacetylation;
	Sources:Amigo / QuickGO
Orthologs
	53615
	17192
	ENSG00000071655
	ENSMUSG00000035478
	O95983
	Q9Z2D8
	NM_003926; NM_001281453; NM_001281454
	NM_013595; NM_001306143
	NP_001268382; NP_001268383
	NP_001293072; NP_038623
	Wikidata
View/Edit Human	View/Edit Mouse

Methyl-CpG-binding domain protein 3 is a protein that in humans is encoded by the MBD3 gene.