MBOAT
| MBOAT | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | MBOAT | ||||||||
| Pfam | PF03062 | ||||||||
| Pfam clan | CL0517 | ||||||||
| InterPro | IPR004299 | ||||||||
| |||||||||
| MBOAT_2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | MBOAT_2 | ||||||||
| Pfam | PF13813 | ||||||||
| Pfam clan | CL0517 | ||||||||
| |||||||||
The MBOAT (membrane bound O-acyl transferase) family of membrane proteins is a family of various acyltransferase enzymes. All family members contain multiple transmembrane domains and most carry two conserved residues, a conserved histidine (His) embedded in a hydrophobic stretch of residues and an asparagine (Asn) or histidine within a more hydrophilic region some 30-50 residues upstream.
MBOAT enzymes catalyze the transfer of an acyl group from an acyl-coenzyme or accessory protein to one of several different substrates. The family is found from bacteria to eukaryotes.
The family may be grouped into three categories, according to function:
- enzymes involved in neutral lipid biosynthesis;
- enzymes involved in protein/peptide acylation;
- enzymes involved in phospholipid re-modelling.