MCF2L

MCF2L
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1KZ7, 1KZG, 1LB1, 1RJ2
Identifiers
Aliases	MCF2L, ARHGEF14, DBS, OST, MCF.2 cell line derived transforming sequence like
External IDs	OMIM: 609499; MGI: 103263; HomoloGene: 11804; GeneCards: MCF2L; OMA:MCF2L - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	113,099,742 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	13,020,905 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; right frontal lobe; ; paraflocculus of cerebellum; ; pituitary gland; ; apex of heart; ; anterior pituitary; ; C1 segment; ; Brodmann area 9; ; prefrontal cortex; ; primary visual cortex;
	Top expressed in
	olfactory epithelium; ; neural layer of retina; ; cerebellar cortex; ; primary visual cortex; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; pituitary gland; ; lobe of cerebellum; ; cerebellar vermis; ; islet of Langerhans;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	phosphatidylinositol binding; lipid binding; guanyl-nucleotide exchange factor activity;
Cellular component	cytoplasm; extrinsic component of cytoplasmic side of plasma membrane; cytosol; plasma membrane; membrane; endomembrane system; extracellular space;
Biological process	positive regulation of Rho protein signal transduction; regulation of Rho protein signal transduction; intracellular signal transduction; regulation of small GTPase mediated signal transduction; positive regulation of apoptotic process; G protein-coupled receptor signaling pathway; regulation of molecular function;
	Sources:Amigo / QuickGO
Orthologs
	23263
	17207
	ENSG00000126217
	ENSMUSG00000031442
	O15068
	Q64096
NM_001112732; NM_024979; NM_001320815; NM_001320816; NM_001320817;
	NM_001366644; NM_001366645; NM_001366646
	NM_001159485; NM_001159486; NM_178076
NP_001106203; NP_001307744; NP_001307745; NP_001307746; NP_079255;
	NP_001353573; NP_001353574; NP_001353575
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Guanine nucleotide exchange factor DBS is a protein that in humans is encoded by the MCF2L gene.