Melanin-concentrating hormone receptor 2

MCHR2
Identifiers
Aliases	MCHR2, GPR145, GPRv17, MCH-2R, MCH-R2, MCH2, MCH2R, MCHR-2, SLT, melanin concentrating hormone receptor 2
External IDs	OMIM: 606111; HomoloGene: 50004; GeneCards: MCHR2; OMA:MCHR2 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	99,994,247 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; Brodmann area 46; ; testicle; ; right frontal lobe; ; superior frontal gyrus; ; anterior cingulate cortex; ; primary visual cortex; ; postcentral gyrus;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled peptide receptor activity; G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	phospholipase C-activating G protein-coupled receptor signaling pathway; neuropeptide signaling pathway; signal transduction; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	84539
	n/a
	ENSG00000152034
	n/a
	Q969V1
	n/a
	NM_032503; NM_001040179
	n/a
	NP_001035269; NP_115892
	n/a
	Wikidata
View/Edit Human

Melanin-concentrating hormone receptor 2 (MCH₂) also known as G-protein coupled receptor 145 (GPR145) is a protein that in humans is encoded by the MCHR2 gene.

MCH₂ is also found in dogs, ferrets, and some other primates and carnivores, but is not found in mice or rats. This has delayed research into the receptor as a therapeutic target, due to most early pharmaceutical research usually being conducted in small mammals such as mice, rats or rabbits which lack the MCH₂ gene and its receptor product.