MCM10

MCM10
Identifiers
Aliases	MCM10, CNA43, DNA43, PRO2249, minichromosome maintenance 10 replication initiation factor, IMD80
External IDs	OMIM: 609357; MGI: 1917274; HomoloGene: 41275; GeneCards: MCM10; OMA:MCM10 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	13,211,110 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	5,017,602 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; ventricular zone; ; ganglionic eminence; ; gonad; ; amniotic fluid; ; bone marrow; ; testicle; ; gingival epithelium; ; trabecular bone; ; bone marrow cells;
	Top expressed in
	zygote; ; secondary oocyte; ; primary oocyte; ; otic placode; ; tail of embryo; ; left lobe of liver; ; otic vesicle; ; primitive streak; ; genital tubercle; ; epiblast;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; DNA replication origin binding; single-stranded DNA binding; identical protein binding; metal ion binding; enzyme binding; double-stranded DNA binding;
Cellular component	nucleolus; nucleoplasm; replication fork protection complex; nucleus;
Biological process	DNA replication; cellular response to DNA damage stimulus; cell population proliferation; DNA replication initiation; G1/S transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	55388
	70024
	ENSG00000065328
	ENSMUSG00000026669
	Q7L590
	Q0VBD2
	NM_018518; NM_182751
	NM_027290; NM_001305259
	NP_060988; NP_877428
	NP_001292188; NP_081566
	Wikidata
View/Edit Human	View/Edit Mouse

Protein MCM10 homolog is a protein that in humans is encoded by the MCM10 gene. It is essential for activation of the Cdc45:Mcm2-7:GINS helicase, and thus required for proper DNA replication.