MED12

MED12
Identifiers
Aliases	MED12, ARC240, CAGH45, FGS1, HOPA, MED12S, OHDOX, OKS, OPA1, TNRC11, TRAP230, mediator complex subunit 12, Kto, HDKR
External IDs	OMIM: 300188; MGI: 1926212; HomoloGene: 68441; GeneCards: MED12; OMA:MED12 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	71,144,103 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	100,341,071 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; left ovary; ; right ovary; ; left adrenal gland; ; left adrenal cortex; ; body of uterus; ; right uterine tube; ; spleen; ; canal of the cervix; ; right lobe of thyroid gland;
	Top expressed in
	bone marrow; ; tail of embryo; ; islet of Langerhans; ; spleen; ; genital tubercle; ; neural layer of retina; ; thymus; ; adrenal gland; ; cerebellar cortex; ; granulocyte;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; transcription coactivator activity; beta-catenin binding; protein domain specific binding; ubiquitin protein ligase activity; transcription coregulator activity; transcription factor binding; chromatin binding; thyroid hormone receptor binding; protein C-terminus binding; protein binding; nuclear receptor coactivator activity; vitamin D receptor binding; signaling receptor activity;
Cellular component	membrane; ubiquitin ligase complex; mediator complex; nucleus; nucleoplasm;
Biological process	somitogenesis; androgen receptor signaling pathway; endoderm development; regulation of transcription, DNA-templated; embryonic organ development; embryonic neurocranium morphogenesis; axis elongation involved in somitogenesis; regulation of transcription by RNA polymerase II; Schwann cell development; negative regulation of Wnt signaling pathway; intracellular steroid hormone receptor signaling pathway; transcription, DNA-templated; stem cell population maintenance; positive regulation of transcription, DNA-templated; Wnt signaling pathway, planar cell polarity pathway; heart development; neural tube closure; embryonic brain development; protein ubiquitination; neural tube development; spinal cord development; post-anal tail morphogenesis; canonical Wnt signaling pathway; oligodendrocyte development; transcription initiation from RNA polymerase II promoter; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	9968
	59024
	ENSG00000184634
	ENSMUSG00000079487
	Q93074
	A2AGH6
	NM_005120
	NM_021521
	NP_005111
	NP_067496
	Wikidata
View/Edit Human	View/Edit Mouse

Mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae), also known as MED12, is a human gene found on the X chromosome.