MFGE8

MFGE8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2L9L
Identifiers
Aliases	MFGE8, milk fat globule-EGF factor 8 protein, BA46, EDIL1, HMFG, HsT19888, MFG-E8, MFGM, OAcGD3S, SED1, SPAG10, hP47, milk fat globule EGF and factor V/VIII domain containing
External IDs	OMIM: 602281; MGI: 102768; HomoloGene: 4334; GeneCards: MFGE8; OMA:MFGE8 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	88,913,468 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	78,798,808 bp
RNA expression pattern
	Top expressed in
	Descending thoracic aorta; ; ascending aorta; ; right coronary artery; ; left coronary artery; ; popliteal artery; ; tibial arteries; ; stromal cell of endometrium; ; left uterine tube; ; apex of heart; ; body of uterus;
	Top expressed in
	lactiferous gland; ; mesenteric lymph nodes; ; tunica media of zone of aorta; ; entorhinal cortex; ; choroid plexus of fourth ventricle; ; perirhinal cortex; ; lacrimal gland; ; ascending aorta; ; molar; ; neural layer of retina;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phosphatidylserine binding; phosphatidylethanolamine binding; integrin binding; extracellular matrix structural constituent;
Cellular component	external side of plasma membrane; extrinsic component of plasma membrane; extracellular region; extracellular exosome; extracellular matrix; extracellular vesicle; membrane; extracellular space; endoplasmic reticulum lumen; collagen-containing extracellular matrix;
Biological process	phagocytosis, recognition; angiogenesis; positive regulation of phagocytosis; positive regulation of apoptotic cell clearance; phagocytosis, engulfment; cell adhesion; single fertilization; viral process; post-translational protein modification; apoptotic cell clearance;
	Sources:Amigo / QuickGO
Orthologs
	4240
	17304
	ENSG00000140545
	ENSMUSG00000030605
	Q08431
	P21956
	NM_001114614; NM_001310319; NM_001310320; NM_001310321; NM_005928
	NM_001045489; NM_008594
	NP_001108086; NP_001297248; NP_001297249; NP_001297250; NP_005919
	NP_001038954; NP_032620
	Wikidata
View/Edit Human	View/Edit Mouse

Milk fat globule-EGF factor 8 protein (Mfge8), also known as lactadherin, is a protein that in humans is encoded by the MFGE8 gene.