Microsomal glutathione S-transferase 1

MGST1
Identifiers
Aliases	MGST1, GST12, MGST, MGST-I, microsomal glutathione S-transferase 1
External IDs	OMIM: 138330; MGI: 1913850; HomoloGene: 10544; GeneCards: MGST1; OMA:MGST1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	16,609,259 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	138,133,753 bp
RNA expression pattern
	Top expressed in
	right adrenal gland; ; right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; right lobe of liver; ; mucosa of ileum; ; adipose tissue; ; abdominal fat; ; subcutaneous adipose tissue; ; pericardium;
	Top expressed in
	left lobe of liver; ; tunica adventitia of aorta; ; transitional epithelium of urinary bladder; ; right lung lobe; ; granulocyte; ; subcutaneous adipose tissue; ; white adipose tissue; ; intercostal muscle; ; brown adipose tissue; ; nose;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; identical protein binding; glutathione binding; protein homodimerization activity; glutathione peroxidase activity; protein binding; glutathione transferase activity; prostaglandin-E synthase activity;
Cellular component	integral component of membrane; mitochondrion; nucleus; peroxisomal membrane; apical part of cell; intracellular membrane-bounded organelle; membrane; endoplasmic reticulum; endoplasmic reticulum membrane; mitochondrial outer membrane; plasma membrane; azurophil granule membrane;
Biological process	xenobiotic metabolic process; response to lipopolysaccharide; protein homotrimerization; Leydig cell differentiation; cellular response to lipid hydroperoxide; glutathione derivative biosynthetic process; response to organonitrogen compound; cellular oxidant detoxification; neutrophil degranulation; prostaglandin biosynthetic process; glutathione metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	4257
	56615
	ENSG00000008394
	ENSMUSG00000008540
	P10620
	Q91VS7
NM_001260511; NM_001260512; NM_001267598; NM_020300; NM_145764;
	NM_145791; NM_145792
	NM_019946; NM_001347489; NM_001361308; NM_001361309; NM_001361307
NP_001247440; NP_001247441; NP_001254527; NP_064696; NP_665707;
	NP_665734; NP_665735
	NP_001334418; NP_064330; NP_001348237; NP_001348238; NP_001348236
	Wikidata
View/Edit Human	View/Edit Mouse

Microsomal glutathione S-transferase 1 is an enzyme that in humans is encoded by the MGST1 gene.