MIPEP

MIPEP
Identifiers
Aliases	MIPEP, HMIP, MIP, mitochondrial intermediate peptidase, COXPD31
External IDs	OMIM: 602241; MGI: 1917728; HomoloGene: 4337; GeneCards: MIPEP; OMA:MIPEP - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	23,889,400 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	61,142,927 bp
RNA expression pattern
	Top expressed in
	right auricle of heart; ; apex of heart; ; gonad; ; left ventricle; ; right uterine tube; ; skin of abdomen; ; skin of leg; ; bronchial epithelial cell; ; olfactory zone of nasal mucosa; ; mucosa of transverse colon;
	Top expressed in
	seminiferous tubule; ; spermatid; ; interventricular septum; ; myocardium of ventricle; ; otolith organ; ; utricle; ; oocyte; ; primary oocyte; ; spermatocyte; ; secondary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptidase activity; hydrolase activity; metallopeptidase activity; metal ion binding; metalloendopeptidase activity;
Cellular component	mitochondrial matrix; mitochondrion;
Biological process	peptide metabolic process; proteolysis; protein processing involved in protein targeting to mitochondrion;
	Sources:Amigo / QuickGO
Orthologs
	4285
	70478
	ENSG00000027001
	ENSMUSG00000021993
	Q99797
	A6H611
	NM_005932
	NM_027436
	NP_005923
	NP_081712
	Wikidata
View/Edit Human	View/Edit Mouse

Mitochondrial intermediate peptidase is an enzyme that in humans is encoded by the MIPEP gene. This protein is a critical component of human mitochondrial protein import machinery involved in the maturing process of nuclear coded mitochondrial proteins that with a mitochondrial translocation peptide, especially those OXPHOS-related proteins.