Lens fiber major intrinsic protein

MIP
Identifiers
Aliases	MIP, AQP0, CTRCT15, LIM1, MIP26, MP26, major intrinsic protein of lens fiber
External IDs	OMIM: 154050; MGI: 96990; HomoloGene: 40627; GeneCards: MIP; OMA:MIP - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	56,469,166 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	128,067,681 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; right lobe of liver; ; apex of heart; ; right adrenal cortex; ; right testis; ; left testis; ; left adrenal gland; ; body of pancreas; ; left adrenal cortex;
	Top expressed in
	lens; ; epithelium of lens; ; set of lens fibers; ; neural layer of retina; ; ciliary body; ; embryo; ; morula; ; tail of embryo; ; blastocyst; ; conjunctival fornix;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calmodulin binding; structural constituent of eye lens; water channel activity; channel activity;
Cellular component	integral component of membrane; membrane; plasma membrane; cell junction; apical plasma membrane; endoplasmic reticulum; gap junction; integral component of plasma membrane;
Biological process	response to stimulus; water transport; ion transmembrane transport; lens development in camera-type eye; protein homotetramerization; visual perception; positive regulation of cell adhesion; gap junction-mediated intercellular transport; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	4284
	17339
	ENSG00000135517
	ENSMUSG00000025389
	P30301
	P51180
	NM_012064
	NM_008600
	NP_036196
	NP_032626
	Wikidata
View/Edit Human	View/Edit Mouse

Lens fiber major intrinsic protein also known as aquaporin-0 is a protein that in humans is encoded by the MIP gene.