Ki-67 (protein)

MKI67
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1R21, 2AFF
Identifiers
Aliases	MKI67, marker of proliferation Ki-67, KIA, MIB-, MIB-1, PPP1R105
External IDs	OMIM: 176741; MGI: 106035; HomoloGene: 1814; GeneCards: MKI67; OMA:MKI67 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	128,126,423 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	135,318,090 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; bone marrow cells; ; gonad; ; trabecular bone; ; tendon of biceps brachii; ; thymus; ; stromal cell of endometrium; ; mucosa of transverse colon; ; testicle;
	Top expressed in
	fetal liver hematopoietic progenitor cell; ; tibiofemoral joint; ; human fetus; ; Paneth cell; ; genital tubercle; ; vas deferens; ; hair follicle; ; primitive streak; ; tail of embryo; ; efferent ductule;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; protein C-terminus binding; protein binding; ATP binding; DNA binding; RNA binding;
Cellular component	cytoplasm; membrane; chromosome; nucleolus; chromosome, centromeric region; nucleus; condensed chromosome; nuclear body;
Biological process	cellular response to heat; response to organic cyclic compound; DNA metabolic process; animal organ regeneration; hyaluronan metabolic process; cell cycle; regulation of chromosome segregation; cell population proliferation; regulation of mitotic nuclear division; regulation of chromatin organization; meiosis;
	Sources:Amigo / QuickGO
Orthologs
	4288
	17345
	ENSG00000148773
	ENSMUSG00000031004
	P46013
	E9PVX6
	NM_001145966; NM_002417
	NM_001081117
	NP_001139438; NP_002408
	NP_001074586
	Wikidata
View/Edit Human	View/Edit Mouse

Antigen Kiel 67, also known as Ki-67 or MKI67 (marker of proliferation Kiel 67), is a protein that in humans is encoded by the MKI67 gene (antigen identified by monoclonal antibody Ki-67).