MKNK1

MKNK1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2HW6, 2Y9Q
Identifiers
Aliases	MKNK1, MNK1, MAP kinase interacting serine/threonine kinase 1, MAPK interacting serine/threonine kinase 1
External IDs	OMIM: 606724; MGI: 894316; HomoloGene: 37838; GeneCards: MKNK1; OMA:MKNK1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	46,616,843 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	115,736,447 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; spleen; ; Descending thoracic aorta; ; blood; ; gastric mucosa; ; secondary oocyte; ; muscle layer of sigmoid colon; ; right coronary artery; ; upper lobe of left lung; ; monocyte;
	Top expressed in
	granulocyte; ; secondary oocyte; ; stroma of bone marrow; ; primary oocyte; ; neural layer of retina; ; thymus; ; lip; ; muscle of thigh; ; pancreas; ; dentate gyrus of hippocampal formation granule cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; calcium-dependent protein serine/threonine kinase activity; calmodulin binding; kinase activity; protein binding; calmodulin-dependent protein kinase activity; ATP binding; protein serine/threonine kinase activity; metal ion binding;
Cellular component	cytoplasm; cytosol; nucleoplasm; nucleus;
Biological process	intracellular signal transduction; phosphorylation; protein phosphorylation; protein autophosphorylation; regulation of translation; peptidyl-serine phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	8569
	17346
	ENSG00000079277
	ENSMUSG00000028708
	Q9BUB5
	O08605
NM_001135553; NM_003684; NM_198973; NM_001377337; NM_001377338;
	NM_001377341; NM_001377342; NM_001377343; NM_001377373; NM_001377374; NM_001377375
	NM_001285487; NM_001285488; NM_021461; NM_001355174; NM_001369238
NP_001129025; NP_003675; NP_945324; NP_001364266; NP_001364267;
	NP_001364270; NP_001364271; NP_001364272; NP_001364302; NP_001364303; NP_001364304
	NP_001272416; NP_001272417; NP_067436; NP_001342103; NP_001356167
	Wikidata
View/Edit Human	View/Edit Mouse

MAP kinase-interacting serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the MKNK1 gene.