MLLT3

MLLT3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2LM0, 2MV7, 4TMP, 2N4Q, 5HJB, 5HJD
Identifiers
Aliases	MLLT3, AF9, YEATS3, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3, super elongation complex subunit, MLLT3 super elongation complex subunit
External IDs	OMIM: 159558; MGI: 1917372; HomoloGene: 37933; GeneCards: MLLT3; OMA:MLLT3 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	20,622,499 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	87,951,601 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; rectum; ; Achilles tendon; ; epithelium of colon; ; endothelial cell; ; ventricular zone; ; buccal mucosa cell; ; testicle; ; mucosa of transverse colon; ; stromal cell of endometrium;
	Top expressed in
	tail of embryo; ; genital tubercle; ; zygote; ; metatarsal bones; ; plantaris muscle; ; muscle of thigh; ; extensor digitorum longus muscle; ; intercostal muscle; ; Ileal epithelium; ; triceps brachii muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; chromatin binding; histone binding; lysine-acetylated histone binding; modification-dependent protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	transcription elongation factor complex; extracellular exosome; nucleus; nucleoplasm; chromosome;
Biological process	positive regulation of Wnt signaling pathway, planar cell polarity pathway; regulation of transcription, DNA-templated; negative regulation of canonical Wnt signaling pathway; transcription, DNA-templated; segment specification; anterior/posterior pattern specification; transcription by RNA polymerase II; transcription elongation from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	4300
	70122
	ENSG00000171843
	ENSMUSG00000028496
	P42568
	A2AM29
	NM_004529; NM_001286691
	NM_001286158; NM_027326; NM_029931
	NP_001273620; NP_004520
NP_001273087; NP_081602; NP_084207; NP_001391884; NP_001391885;
	NP_001391886; NP_001391887
	Wikidata
View/Edit Human	View/Edit Mouse

Protein AF-9 is a protein that in humans is encoded by the MLLT3 gene.