Motilin receptor

MLNR
Identifiers
Aliases	MLNR, GPR38, MTLR1, motilin receptor
External IDs	OMIM: 602885; HomoloGene: 74398; GeneCards: MLNR; OMA:MLNR - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	49,222,377 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; bone marrow; ; fundus; ; body of stomach; ; islet of Langerhans; ; blood; ; stromal cell of endometrium; ; right lobe of thyroid gland; ; kidney;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	growth hormone-releasing hormone receptor activity; signal transducer activity; G protein-coupled receptor activity; G protein-coupled peptide receptor activity; hormone binding;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	G protein-coupled receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	2862
	n/a
	ENSG00000102539
	n/a
	O43193
	n/a
	NM_001507
	n/a
	NP_001498
	n/a
	Wikidata
View/Edit Human

Motilin receptor is a G protein-coupled receptor (previously GPCR38) that binds motilin. It was first cloned in 1999 by Merck Laboratories. and scientists have since been searching for compounds to modify its behavior.

The primary structure of the motilin receptor consists of 412 amino acids, while its tertiary structure resembles a golf club. The protein C-terminal protein protects from enzymatic degradation, while the N-terminal is essential for binding.