MNAT1

MNAT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1G25
Identifiers
Aliases	MNAT1, CAP35, MAT1, RNF66, TFB3, CDK activating kinase assembly factor, MNAT1 component of CDK activating kinase
External IDs	OMIM: 602659; MGI: 106207; HomoloGene: 1821; GeneCards: MNAT1; OMA:MNAT1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	60,969,965 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	73,320,762 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; muscle of thigh; ; gastrocnemius muscle; ; olfactory zone of nasal mucosa; ; ventricular zone; ; ganglionic eminence; ; popliteal artery; ; tibial arteries; ; right uterine tube; ; testicle;
	Top expressed in
	tail of embryo; ; epiblast; ; primitive streak; ; embryo; ; embryo; ; lens; ; genital tubercle; ; yolk sac; ; ventricular zone; ; mandibular prominence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ATP-dependent activity, acting on DNA; protein N-terminus binding; metal ion binding; protein binding; RNA polymerase II CTD heptapeptide repeat kinase activity; cyclin-dependent protein serine/threonine kinase activator activity; zinc ion binding;
Cellular component	nucleoplasm; nucleus; cytosol; transcription factor TFIIH holo complex; cyclin-dependent protein kinase activating kinase holoenzyme complex;
Biological process	termination of RNA polymerase I transcription; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of transcription, DNA-templated; adult heart development; regulation of transcription by RNA polymerase II; transcription initiation from RNA polymerase I promoter; transcription elongation from RNA polymerase II promoter; negative regulation of apoptotic process; 7-methylguanosine mRNA capping; transcription by RNA polymerase II; ventricular system development; transcription, DNA-templated; response to calcium ion; cell cycle; transcription-coupled nucleotide-excision repair; transcription initiation from RNA polymerase II promoter; cell population proliferation; DNA repair; positive regulation of transcription by RNA polymerase II; positive regulation of smooth muscle cell proliferation; protein phosphorylation; nucleotide-excision repair, preincision complex assembly; positive regulation of cyclin-dependent protein serine/threonine kinase activity; nucleotide-excision repair; protein-containing complex assembly; G1/S transition of mitotic cell cycle; negative regulation of DNA helicase activity; G2/M transition of mitotic cell cycle; transcription elongation from RNA polymerase I promoter;
	Sources:Amigo / QuickGO
Orthologs
	4331
	17420
	ENSG00000020426
	ENSMUSG00000021103
	P51948
	P51949
	NM_001177963; NM_002431
	NM_008612
	NP_001171434; NP_002422
	NP_032638
	Wikidata
View/Edit Human	View/Edit Mouse

CDK-activating kinase assembly factor MAT1 is an enzyme that in humans is encoded by the MNAT1 gene.